GLP-1 Initiation Common After Bariatric Surgery
GLP-1 initiation was common among patients who underwent bariatric surgery, especially sleeve gastrectomy vs Roux-en-Y gastric bypass.
Glucagon-like peptide-1 (GLP-1) receptor agonist initiation is relatively common after bariatric surgery, occurring among about 1 in 10 individuals within 5 years, with influential factors including sex, type of surgery, diabetes status, and postsurgical weight outcomes, according to study results published in JAMA Surgery.
Researchers performed a retrospective cohort study using deidentified electronic health record data from the TriNetX global research network, covering over 113 million patients.
Adults undergoing bariatric surgery between January 1, 2015 and May 31, 2023 with at least 2 years of postoperative follow-up were included.
GLP-1 initiation was identified using RxNorm codes for semaglutide, liraglutide, tirzepatide, exenatide, lixisenatide, and dulaglutide.
Author's summary: Bariatric surgery often leads to GLP-1 initiation.