The Tijuana Xolos lost 4-3 to Puebla, marking their second consecutive loss away from home.
Club Tijuana has only won one road game this season and is now on a three-game winless streak away from home.
Gilberto Mora returned from the FIFA U-20 World Cup and started in the game, replacing Mourad El Ghezouani.
The game was a tale of two halves, with the first half offering little excitement and no goals.
The team's success has been due to favorable results at home.
Author's summary: Tijuana Xolos struggle on road.