Effect of Intensive Blood Pressure Lowering Treatment on Retinal Microvasculature
A secondary analysis from the ESPRIT study reveals that intensive systolic blood pressure (SBP) management reduces hypertension-mediated retinal microvascular damage in high-risk populations.
Hypertension causes changes in the retinal microvasculature, leading to hypertensive retinopathy. Antihypertensive treatment slows the progression of this condition.
A multicentre, open-label, randomized controlled trial of 2,518 patients (mean age 62.7 ± 6.4 years, 37%) investigated the effects of intensive SBP treatment.
Intensive systolic blood pressure management reduces hypertension-mediated retinal microvascular damage.
Evidence Rating Level: 1 (Excellent)
Author's summary: Intensive blood pressure lowering treatment reduces retinal microvascular damage.