Could Melatonin Be Silently Harming Your Heart?
Learn how scientists uncovered a surprising link between long-term melatonin use and heart failure in chronic insomnia patients.
Marketed as nature’s sleep switch, melatonin has become a nightly habit for millions. But new research presented this week at the American Heart Association’s Scientific Sessions 2025, suggests the supplement may do more than quiet the mind — it could also trouble the heart.
In the review of more than 130,000 adults with insomnia, long-term melatonin use (for a year or more) was linked with a nearly doubled risk of developing heart failure, more than triple the risk of hospitalization for heart failure, and nearly twice the risk of death over five years.
Author's summary: Research links long-term melatonin use to heart failure risks.