Vigorous Anti-Infectious Prophylaxis Reduces Febrile Neutropenia in BR‑Treated Patients With iBC-NHL - Oncology Nurse Advisor

Reducing Febrile Neutropenia in iBC-NHL Patients

Researchers investigated the effectiveness of primary anti-infectious prophylaxis in reducing febrile neutropenia and treatment interruptions in older patients with indolent B-cell non-Hodgkin lymphomas (iBC-NHLs) receiving bendamustine-rituximab (BR) treatment.

Real-world experience in clinical practice shows a gradual transition from multiagent chemo-immunotherapy (rituximab, cyclophosphamide, doxorubicin, oncovin, prednisone [R-CHOP]) to [BR] for frontline treatment of [iBC-NHL]

Vigorous primary anti-infectious prophylaxis significantly reduces the incidence of febrile neutropenia and treatment interruptions in these patients, according to research published in Supportive Care in Cancer.

Author's summary: Prophylaxis reduces febrile neutropenia in iBC-NHL patients.

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Oncology Nurse Advisor Oncology Nurse Advisor — 2025-10-16

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