Researchers investigated the effectiveness of primary anti-infectious prophylaxis in reducing febrile neutropenia and treatment interruptions in older patients with indolent B-cell non-Hodgkin lymphomas (iBC-NHLs) receiving bendamustine-rituximab (BR) treatment.
Real-world experience in clinical practice shows a gradual transition from multiagent chemo-immunotherapy (rituximab, cyclophosphamide, doxorubicin, oncovin, prednisone [R-CHOP]) to [BR] for frontline treatment of [iBC-NHL]
Vigorous primary anti-infectious prophylaxis significantly reduces the incidence of febrile neutropenia and treatment interruptions in these patients, according to research published in Supportive Care in Cancer.
Author's summary: Prophylaxis reduces febrile neutropenia in iBC-NHL patients.